bio-atac-seq-consensus-peakset - Build a consensus ATAC-seq peakset
Build a differential-ready consensus peakset from replicate ATAC-seq peaks using overlap rules, summit re-centering, and fixed-width regions.
Tags
Updated: 2026-10-04Capabilities
Typical Inputs
Typical Outputs
What this skill does
- Pool replicate peak calls
- Recenter peaks on summits
- Rank peaks by significance
- Remove overlapping peaks iteratively
- Apply majority-rule overlap
- Generate fixed-width coordinates
Inputs
- Replicate peak files
- Genome sizes file
- Peak format and summit information
- Sample or condition grouping
- Consensus strategy parameters
Outputs
- Consensus BED peakset
- Fixed-width peak coordinates
- Peak count summary
Requirements
- bedtools 2.31+
- samtools 1.19+
- BEDOPS 2.4.41+
- GenomicRanges 1.54+
- DiffBind 3.12+
- Subread 2.0+
- pybedtools 0.10+
- Genome sizes matching peak coordinates