bio-genome-intervals-coverage-analysis - Calculate depth and coverage across genomic intervals
Calculate read depth and coverage across genomic intervals using bedtools, generate bedGraph files, compute per-base depth, and summarize statistics.
Tags
Updated: 2026-09-19Capabilities
Typical Inputs
Typical Outputs
What this skill does
- Generate bedGraph files
- Compute per-base coverage depth
- Calculate feature coverage statistics
- Count reads across multiple BAMs
Inputs
- BAM alignment files
- BED interval files
- Genome size files
Outputs
- bedGraph files
- Coverage summary files
- Coverage histogram files
Requirements
- bedtools 2.31+
- samtools 1.19+
- numpy 1.26+
- pandas 2.2+
