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ensembl-database - Query Ensembl database REST API for genomic research

Query gene annotations, sequences, variants, orthologs, VEP predictions, and assembly mappings across 250+ species via Ensembl REST API.

Tags

Updated: 2026-09-19

Capabilities

Typical Inputs

Typical Outputs

What this skill does

  • Retrieve gene information
  • Fetch genomic sequences
  • Analyze genetic variants
  • Find orthologs and paralogs
  • Analyze genomic regions
  • Map assembly coordinates

Inputs

  • Gene symbols or Ensembl IDs
  • Genomic region coordinates
  • Variant HGVS notations or rsIDs
  • Species names
  • Genome assembly names

Outputs

  • Gene annotations
  • DNA transcript and protein sequences
  • Variant consequence predictions
  • Ortholog and paralog data
  • Genomic region features
  • Mapped assembly coordinates

Requirements

  • Internet access to Ensembl REST API
  • ensembl_rest Python package or requests library

Source

  • Spec: SKILL.md

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ensembl
genomics
bioinformatics
rest-api
variants
Retrieve gene information
Fetch genomic sequences
Analyze genetic variants
Find orthologs and paralogs
Gene symbols or Ensembl IDs
Genomic region coordinates
Variant HGVS notations or rsIDs
Gene annotations
DNA transcript and protein sequences
Variant consequence predictions