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prs-net-deep-learning-agent - Geometric Deep Learning PRS Prediction

Geometric deep learning for polygenic risk score prediction with gene interaction modeling

Tags

Updated: 2026-03-24

Capabilities

Typical Inputs

Typical Outputs

What this skill does

  • predict disease risk
  • model gene interactions
  • integrate PPI networks
  • identify pathways
  • transfer across ancestries
  • quantify uncertainty
  • calculate risk scores
  • explain predictions

Inputs

  • genotypes
  • PPI network
  • gene mapping
  • training labels
  • GWAS summary

Outputs

  • PRS-Net scores
  • risk percentiles
  • gene importance
  • pathway enrichment
  • module visualizations
  • prediction uncertainty

Requirements

  • Python 3.10+
  • PyTorch
  • PyTorch Geometric
  • NetworkX
  • GPU

Source

  • Spec: SKILL.md

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precision medicine
genomics
deep learning
polygenic risk score
gene networks
disease prediction
cross-ancestry
predict disease risk
model gene interactions
integrate PPI networks
identify pathways
genotypes
PPI network
gene mapping
PRS-Net scores
risk percentiles
gene importance