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universal-single-cell-annotator - Universal Single-Cell Annotator for RNA-seq Data Analysis

A unified interface for annotating single-cell RNA-seq data using Marker Genes, Deep Learning (CellTypist), or LLMs.

Tags

Updated: 2026-02-12

Capabilities

Typical Inputs

Typical Outputs

What this skill does

  • Score cells using marker genes
  • Transfer labels with CellTypist
  • Interpret clusters with LLMs

Inputs

  • Single-cell RNA-seq data
  • Marker gene lists
  • CellTypist models
  • LLM access

Outputs

  • Annotated cell type labels
  • Updated AnnData object

Requirements

  • Python 3.9+ environment
  • Scanpy library
  • Optional CellTypist library

Source

  • Spec: SKILL.md

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Genomics
Single-cell analysis
Cell type annotation
Bioinformatics
Score cells using marker genes
Transfer labels with CellTypist
Interpret clusters with LLMs
Single-cell RNA-seq data
Marker gene lists
CellTypist models
Annotated cell type labels
Updated AnnData object