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bio-epidemiological-genomics-phylodynamics - Time-scaled phylogenies for outbreak analysis

Construct time-scaled phylogenies and infer evolutionary dynamics

Tags

Updated: 2026-03-22

Capabilities

Typical Inputs

Typical Outputs

What this skill does

  • build time-scaled tree
  • estimate divergence times
  • estimate molecular clock rates
  • reconstruct ancestral states
  • analyze population dynamics
  • interpret clock results
  • prepare BEAST2 XML

Inputs

  • sequence alignment
  • phylogenetic tree
  • sampling dates
  • metadata file

Outputs

  • time-scaled phylogeny
  • divergence times
  • molecular clock rates
  • ancestral states
  • population size trajectory

Requirements

  • Python environment
  • BioPython 1.83+
  • TreeTime 0.11+
  • scanpy 1.10+

Source

  • Spec: SKILL.md

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phylogenetics
epidemiology
genomics
molecular clock
outbreak analysis
build time-scaled tree
estimate divergence times
estimate molecular clock rates
reconstruct ancestral states
sequence alignment
phylogenetic tree
sampling dates
time-scaled phylogeny
divergence times
molecular clock rates