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bio-epidemiological-genomics-phylodynamics - Time-scaled Phylogeny and Evolutionary Dynamics Analysis

Construct time-scaled phylogenies and infer evolutionary dynamics using TreeTime and BEAST2 for outbreak analysis

Tags

Updated: 2026-03-22

Capabilities

Typical Inputs

Typical Outputs

What this skill does

  • build time-scaled trees
  • estimate clock rates
  • estimate divergence times
  • reconstruct ancestral sequences
  • analyze population dynamics
  • prepare date files
  • prepare BEAST2 configuration

Inputs

  • sequence alignment file
  • phylogenetic tree file
  • sample dates file
  • states file

Outputs

  • time-scaled phylogenetic tree
  • molecular clock rate
  • ancestral sequences
  • population dynamics data

Requirements

  • Python environment
  • TreeTime 0.11+
  • BioPython 1.83+
  • scanpy 1.10+
  • BEAST2

Source

  • Spec: SKILL.md
epidemiology
genomics
phylogenetics
outbreak analysis
molecular clock
build time-scaled trees
estimate clock rates
estimate divergence times
reconstruct ancestral sequences
sequence alignment file
phylogenetic tree file
sample dates file
time-scaled phylogenetic tree
molecular clock rate
ancestral sequences