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bio-epidemiological-genomics-phylodynamics - Build time-scaled phylogenies for outbreak analysis

Construct time-scaled phylogenies and infer evolutionary dynamics using TreeTime for outbreak analysis

Tags

Updated: 2026-03-22

Capabilities

Typical Inputs

Typical Outputs

What this skill does

  • load Newick tree
  • load alignment file
  • load dates file
  • run molecular clock analysis
  • estimate divergence times
  • estimate clock rate
  • estimate root date
  • reconstruct ancestral sequences
  • analyze discrete traits
  • extract skyline plot
  • interpret clock results

Inputs

  • Newick tree file
  • alignment file
  • dates file
  • metadata file
  • states file

Outputs

  • time-scaled tree
  • clock rate estimate
  • divergence time estimate
  • ancestral sequences
  • skyline plot
  • mugration analysis results

Requirements

  • Python environment
  • BioPython 1.83+
  • TreeTime 0.11+
  • scanpy 1.10+

Source

  • Spec: SKILL.md

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phylogenetics
phylodynamics
molecular clock
outbreak analysis
epidemiology
genomics
evolutionary dynamics
load Newick tree
load alignment file
load dates file
run molecular clock analysis
Newick tree file
alignment file
dates file
time-scaled tree
clock rate estimate
divergence time estimate