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bio-epidemiological-genomics-phylodynamics - Time-scaled phylogenies and evolutionary dynamics

Construct time-scaled phylogenies and infer evolutionary dynamics using TreeTime and BEAST2 for outbreak analysis

Tags

Updated: 2026-03-22

Capabilities

Typical Inputs

Typical Outputs

What this skill does

  • construct time-scaled phylogenies
  • estimate divergence times
  • estimate molecular clock rates
  • estimate ancestral states
  • analyze population dynamics
  • reconstruct ancestral sequences
  • analyze discrete traits

Inputs

  • genetic sequence alignment
  • sample collection dates
  • phylogenetic tree
  • trait states metadata

Outputs

  • time-calibrated phylogenetic tree
  • molecular clock rate estimates
  • ancestral state reconstructions
  • skyline plot data
  • coalescent skyline results

Requirements

  • Python environment
  • TreeTime 0.11+
  • BioPython 1.83+

Source

  • Spec: SKILL.md

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phylogenetics
epidemiology
molecular clock
outbreak analysis
evolutionary dynamics
construct time-scaled phylogenies
estimate divergence times
estimate molecular clock rates
estimate ancestral states
genetic sequence alignment
sample collection dates
phylogenetic tree
time-calibrated phylogenetic tree
molecular clock rate estimates
ancestral state reconstructions