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bio-epidemiological-genomics-phylodynamics - Time-scaled phylogeny and evolutionary dynamics analysis

Construct time-scaled phylogenies and infer evolutionary dynamics using TreeTime and BEAST2

Tags

Updated: 2026-03-22

Capabilities

Typical Inputs

Typical Outputs

What this skill does

  • Build time-scaled phylogenetic trees
  • Estimate molecular clock rates
  • Reconstruct ancestral sequences
  • Analyze discrete traits
  • Extract population size trajectories
  • Prepare BEAST2 XML configuration

Inputs

  • Genetic alignment
  • Phylogenetic tree
  • Sample dates
  • Location states
  • BEAST2 XML template

Outputs

  • Time-scaled phylogenetic tree
  • Ancestral sequences
  • Molecular clock rate
  • Coalescent skyline
  • BEAST2 XML configuration

Requirements

  • Python 3.x
  • BioPython 1.83+
  • TreeTime 0.11+
  • BEAST2

Source

  • Spec: SKILL.md

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phylogenetics
phylodynamics
genomics
epidemiology
evolutionary-analysis
molecular-clock
bioinformatics
Build time-scaled phylogenetic trees
Estimate molecular clock rates
Reconstruct ancestral sequences
Analyze discrete traits
Genetic alignment
Phylogenetic tree
Sample dates
Time-scaled phylogenetic tree
Ancestral sequences
Molecular clock rate