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reactome-database - Query Reactome Pathway Database

Query Reactome REST API for pathway analysis, enrichment, gene-pathway mapping, and molecular interactions

Tags

Updated: 2026-03-25
pathway analysissystems biologygene enrichmentmolecular interactionsbioinformaticsREST API

Capabilities

Query pathway informationRetrieve pathway hierarchiesQuery specific entitiesGet participating molecules

Typical Inputs

Gene identifiersProtein identifiersExpression data files

Typical Outputs

Pathway informationAnalysis resultsStatistical metrics

What this skill does

  • Query pathway information
  • Retrieve pathway hierarchies
  • Query specific entities
  • Get participating molecules
  • Perform enrichment analysis
  • Analyze expression data
  • Compare species pathways
  • Map genes to pathways
  • Submit gene lists
  • Retrieve analysis results

Inputs

  • Gene identifiers
  • Protein identifiers
  • Expression data files
  • Pathway IDs
  • Entity IDs
  • Gene lists
  • TSV data files

Outputs

  • Pathway information
  • Analysis results
  • Statistical metrics
  • Pathway hierarchies
  • Molecule lists
  • Analysis tokens

Requirements

  • Internet connection
  • REST API access
  • Supported identifier formats

Source

  • Spec: SKILL.md

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