bio-chip-seq-motif-analysis - ChIP-seq/ATAC-seq Motif Analysis
Identify DNA sequence motifs enriched in genomic peak data using HOMER and MEME
Tags
Updated: 2026-05-11Capabilities
Typical Inputs
Typical Outputs
What this skill does
- find enriched motifs
- compare motifs to database
- scan genome for matches
- extract sequences from peaks
- run de novo discovery
- create custom motifs
- generate motif logos
- visualize motif results
Inputs
- ChIP-seq peaks
- ATAC-seq peaks
- genome assembly
- background regions
- BED files
- motif database
- reference genome FASTA
Outputs
- motif files
- enrichment statistics
- HTML reports
- annotated peak files
- motif occurrence sites
- sequence logos
- P-value results
Requirements
- HOMER installed
- MEME suite installed
- bedtools installed
- genome configured
- motif database
- Python (optional)