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bio-metagenomics-functional-profiling - Metagenomic Functional Profiling Tool

Profile functional potential of metagenomes using HUMAnN3 to obtain pathway and gene family abundances.

Tags

Updated: 2026-03-20
HUMAnN3CLIfunctional profilingmetagenomicspathway analysisgene family analysis

Capabilities

run HUMAnN3download databasesprocess samplesgenerate gene families

Typical Inputs

metagenomic sequencing datadatabase filestaxonomic profiles

Typical Outputs

gene family abundance tablespathway abundance tablespathway coverage tables

What this skill does

  • run HUMAnN3
  • download databases
  • process samples
  • generate gene families
  • generate pathway abundance
  • normalize tables
  • regroup gene families
  • split stratified tables
  • join tables
  • create barplots
  • calculate pathway coverage

Inputs

  • metagenomic sequencing data
  • database files
  • taxonomic profiles
  • metadata

Outputs

  • gene family abundance tables
  • pathway abundance tables
  • pathway coverage tables
  • merged tables
  • normalized tables
  • regrouped tables
  • barplots
  • heatmaps

Requirements

  • conda or bioconda environment
  • database files
  • computational resources

Source

  • Spec: SKILL.md

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