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geo-database - Search and retrieve NCBI GEO genomics data

Search NCBI GEO for gene expression and functional genomics datasets, retrieve metadata and expression data, and download associated files.

Tags

Updated: 2026-10-19

Capabilities

Typical Inputs

Typical Outputs

What this skill does

  • Search GEO datasets
  • Search gene expression profiles
  • Retrieve GEO metadata
  • Download GEO datasets
  • Parse GEO series
  • Extract expression matrices
  • Filter samples by metadata
  • Fetch supplementary files

Inputs

  • GEO search queries
  • GEO accession identifiers
  • Gene names
  • Organism names
  • Experimental conditions
  • Download directories
  • NCBI Entrez email

Outputs

  • Search result records
  • GEO metadata
  • Expression matrices
  • Downloaded GEO files
  • Filtered sample subsets
  • Expression profile records

Requirements

  • Internet access
  • Python environment
  • GEOparse library
  • Biopython library
  • NCBI Entrez email

Source

  • Spec: SKILL.md

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NCBI GEO
gene expression
functional genomics
transcriptomics
RNA-seq
microarray
bioinformatics
Search GEO datasets
Search gene expression profiles
Retrieve GEO metadata
Download GEO datasets
GEO search queries
GEO accession identifiers
Gene names
Search result records
GEO metadata
Expression matrices