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Skills tagged: chromatin structure

Browse skills that share this tag.

  • bio-hi-c-analysis-compartment-analysis - Identify A/B compartments from Hi-C data with cooltools
    Hi-CA/B compartmentscooltoolschromatin structure

    ★ 1 · Updated 2026-09-19

    Detects A/B chromatin compartments from Hi-C contact matrices using cooltools eigenvector decomposition and quantifies compartmentalization strength.

    ⚙ Compute compartment eigenvectors⚙ Orient compartments using GC content⚙ Extract AB compartment calls
  • nested-TAD-detection - Detect Nested TAD Structures from Hi-C Data Using OnTAD
    Hi-CTAD detectionOnTADnested TAD

    ★ 13 · Updated 2026-06-30

    Detects hierarchical (nested) TAD structures from Hi-C contact maps in .cool, .mcool, or .hic format using OnTAD, extracting per-chromosome dense matrices and generating standardized TAD call files.

    ⚙ list mcool resolutions⚙ harmonize chromosome names⚙ dump chromosome information